American Brain Foundation

Cure One, Cure Many

Minneapolis, MN   |  www.AmericanBrainFoundation.org

Mission

The American Brain Foundation brings researchers and donors together in the relentless pursuit of prevention, improved treatments, and cures for brain diseases and disorders. We invest in research across the whole spectrum of brain disease, including ALS, Alzheimer’s disease and other dementias, multiple sclerosis, Parkinson’s disease, neuromuscular disease, epilepsy, and more. We know brain diseases are interconnected, and our innovative, whole-brain approach gives us an edge in understanding and combating them.

Ruling year info

1993

Principal Officer

Jane Ransom

Main address

201 Chicago Avenue

Minneapolis, MN 55415 USA

Show more contact info

Formerly known as

American Academy of Neurology Foundation

EIN

41-1717098

NTEE code info

Neurology, Neuroscience (G96)

IRS filing requirement

This organization is required to file an IRS Form 990 or 990-EZ.

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Communication

Blog

Programs and results

What we aim to solve

SOURCE: Self-reported by organization

Brain diseases such as Alzheimer’s and Parkinson’s disease, epilepsy, stroke and migraine affect 2 billion people worldwide. These diseases are among the leading causes of disability in the world. Another 100 million Americans live with mental health disorders and chronic pain, both of which are associated with functional and structural changes within the brain. As a result, there are very few among us who are not directly or indirectly touched by brain disease. This makes our mission to defeat brain disease and find cures critical.

Our programs

SOURCE: Self-reported by organization

What are the organization's current programs, how do they measure success, and who do the programs serve?

Cure One, Cure Many Program

The American Brain Foundation’s Cure One, Cure Many program supports breakthrough research in brain disease. The program provides large-scale, catalyst funding to the world’s top researchers who are pursuing the most innovative, cross-cutting approaches to finding diagnoses, treatments, and cures for brain disease. The program targets research topics that cut across multiple disease areas.

The program has multiple research awards, including an annual Cure One, Cure Many Award. The 2022 Cure One, Cure Many Award is a research award for early diagnosis of Lewy body dementia (LBD). In partnership with the Alzheimer’s Association, The Michael J. Fox Foundation for Parkinson’s Research, and the American Academy of Neurology, the American Brain Foundation is seeking to accelerate progress in the diagnosis of Lewy body dementia (LBD). LBD is the most common form of dementia after Alzheimer’s disease. Currently, LBD can only be definitively diagnosed with a brain autopsy after death. As a result of a delay in diagnosis and misdiagnosis, people with LBD and their caregivers endure daily challenges and uncertainty. The goal of the 2022 Cure One, Cure Many Award is to attract the best minds in brain disease research to find a biomarker (diagnostic test) for LBD.

Population(s) Served

The American Brain Foundation’s Next Generation Research Grants fund and support innovative investigations by the best and brightest early-career researchers. Our Next Generation Research Grants have provided millions of dollars to support the next generation of clinical neuroscience researchers in all areas of brain disease, encouraging passion for research and laying the groundwork for future success. Funding research across a broad spectrum of the brain is our best hope for finding better treatments, prevention, and cures for brain diseases and disorders.

• Over $33 million have been raised for Next Generation Research grants.
• 270 researchers have received scholarships and funding.
• 86% of grant recipients have gone on to secure funding from the NIH and other national funders.


Population(s) Served

Our brains are the most complex organism in the known universe. There are over 600 diseases of the brain and nervous system, such as Alzheimer’s, multiple sclerosis, stroke, epilepsy, Parkinson’s, brain cancer, and migraine. Unfortunately, most of these diseases do not have a cure.

What many people don’t realize is that these brain diseases are interrelated by common biological mechanisms, and if we can find those connections, we won’t just find a cure for one brain disease, we will find a cure for many diseases.

The American Brain Foundation is on a mission to raise awareness about brain disease and the need for research. We are committed to sharing valuable and trustworthy resources, including recaps of groundbreaking research in the world of neurology, stories from those impacted by brain disease, and information and facts about brain diseases and disorders.

Population(s) Served

Where we work

Our results

SOURCE: Self-reported by organization

How does this organization measure their results? It's a hard question but an important one.

Total dollar amount active for brain research

This metric is no longer tracked.
Totals By Year
Type of Metric

Output - describing our activities and reach

Direction of Success

Increasing

Number of brain diseases and neurological conditions addressed through research projects funded by the American Brain Foundation

This metric is no longer tracked.
Totals By Year
Type of Metric

Output - describing our activities and reach

Direction of Success

Holding steady

Our Sustainable Development Goals

SOURCE: Self-reported by organization

Learn more about Sustainable Development Goals.

Goals & Strategy

SOURCE: Self-reported by organization

Learn about the organization's key goals, strategies, capabilities, and progress.

Charting impact

Four powerful questions that require reflection about what really matters - results.

Funding research across a broad spectrum of the brain and nervous system is our best hope for finding better treatments, prevention, and cures for the brain diseases. That is why the American Brain Foundation has invested millions of dollars to support innovative scientific investigations by the best and the brightest researchers. We hope to continue to grow and expand these programs through increased awareness around our research funding and deepened partnerships with new organizational and individual partners.

The American Brain Foundation focuses on expanding opportunities for early-career clinician-scientists, developing research on healthcare disparities in neurology, and creating special research initiatives to have an impact on multiple brain diseases simultaneously.

The American Brain Foundation partners with the most respected organizations in the neuroscience community working to defeat specific diseases of the brain and nervous system. We are honored to partner with these leaders in the brain disease space.

All research funded by the American Brain Foundation is selected by our panel of experts on our Research Advisory Committee, and our founder and research partner, the American Academy of Neurology, the world's largest association of neurologists and neuroscientists. This unique partnership allows us access the best and brightest minds to source the most high-risk high-reward research on brain disease.

Since 1992, we have been awarding grants in every area of brain disease, investing more than $33 million in research and granting scholarships and funding to more than 270 researchers to date. 86% of our researchers go on to secure funding from the NIH and other national funders and have lifelong research careers.

Financials

American Brain Foundation
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Operations

The people, governance practices, and partners that make the organization tick.

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Connect with nonprofit leaders

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  • Analyze a variety of pre-calculated financial metrics
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American Brain Foundation

Board of directors
as of 12/01/2021
SOURCE: Self-reported by organization
Board chair

Dr. David Dodick

Mayo Clinic

John Mazziotta

Robert Griggs

Catherine Rydell

David Eagleman

James Essey

Shafali Jeste

Ralph Jozefowicz

Jeffrey Rosenfeld

Jane Ransom

Ralph Sacco

Martin Shenkman

Lisa Shulman

Ben Utecht

Joseph Sirven

Kevin Goodno

Susan Schneider Williams

A. Gordon Smith

Dan Gasby

Organizational demographics

SOURCE: Self-reported; last updated 8/12/2021

Who works and leads organizations that serve our diverse communities? GuideStar partnered on this section with CHANGE Philanthropy and Equity in the Center.

Leadership

The organization's leader identifies as:

Race & ethnicity
White/Caucasian/European
Gender identity
Female

Race & ethnicity

Gender identity

 

Sexual orientation

No data

Disability

No data