St. Jude Children's Research Hospital

Finding cures. Saving children.

aka St. Jude Children's Research Hospital   |   Memphis, TN   |


The mission of St. Jude Children’s Research Hospital is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. Consistent with the vision of our founder Danny Thomas, no child is denied treatment based on race, religion or a family's ability to pay. Families never receive a bill from St. Jude for treatment, travel, housing or food – so they can focus on helping their child live.

Ruling year info


President and CEO

James R. Downing MD

Main address

262 Danny Thomas Place

Memphis, TN 38105 USA

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NTEE code info

Hospital (Specialty) (E24)

Pediatrics Research (H98)

Biological & Life Sciences (U50)

IRS filing requirement

This organization is required to file an IRS Form 990 or 990-EZ.

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Programs and results

What we aim to solve

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Our programs

SOURCE: Self-reported by organization

What are the organization's current programs, how do they measure success, and who do the programs serve?

Care for Children with Catastrophic Diseases

Over 7,800 patients are seen at St. Jude yearly. Most are treated on an outpatient basis, which helps them maintain a sense of normalcy with their families. In addition to the major clinics and treatment areas, an eye clinic, dental clinic, pharmacy, and rehabilitation services are included. The hospital maintains 60 beds for patients requiring hospitalization during treatment. *St. Jude has treated children from all 50 states and all over the world. *Patients are accepted by physician referral based on the patient's eligibility for an ongoing treatment study, regardless of race, sex, ethnicity, religion, or their inability to pay. *We are the only pediatric research center where families never pay for treatment not covered by insurance, and families without insurance are never asked to pay. *More than 85 cents of every dollar we received during the last three years has gone directly to patient care, research, education and training.

Population(s) Served
Children and youth

St. Jude is one of the world's premier biomedical research centers, established with one collaborative goal in mind: finding cures and saving children. Research is directed at understanding the molecular, genetic and chemical bases of catastrophic diseases in children, finding new life-saving treatments for such diseases and promoting their prevention. *We are the first and only cancer center solely focused on pediatric cancer to be designated as a National Cancer Institute Comprehensive Cancer Center. *St. Jude was designated as one of six Centers of Excellence for Influenza Research and Surveillance. *We are the only pediatric research center with an on-site facility for producing highly specialized medicines and vaccines. *St. Jude has one of the largest pediatric treatment and research programs for sickle cell disease in the country. *We are the only pediatric cancer center with a department dedicated to the discovery of new drugs for childhood catastrophic diseases.

Population(s) Served
People with diseases and illnesses

At St. Jude we offer support for every member of the family - all family members can benefit from the psychological, spiritual, developmental and social support offered by the staff and even other families at St. Jude. We believe that caring for the social, psychological, and living needs of a patient and family is just as important as the physical care. We provide families resources to alleviate the many burdens that accompany the diagnosis of a catastrophic pediatric disease. *Our Child Life Program offers services and plans events for the children to help them live as close to a normal life as possible while going through treatment. *We have a School Program onsite that helps children keep up with schoolwork and gives them the sense of a normal routine. *We provide food, transportation and housing free of charge. *There are social workers, psychologists and chaplains on staff who can provide counseling to patients, siblings and parents to help them cope.

Population(s) Served

A diverse but unified group of researchers and clinicians from more than 31 countries form the community of postdoctoral fellows at St. Jude. Each works diligently to strengthen and support the bridge between research and patient care, so the latest cutting-edge breakthroughs in our research laboratories can be transformed into effective treatment for our patients. *St. Jude employs more than 250 clinical fellows, most in three-to-five-year study programs. *Approximately 80 percent of the constantly-rotating group of clinical fellows comes from countries outside of the United States. *St. Jude's Academic Program recruitment team scours the planet for the best and brightest candidates. *St. Jude's research fellows shadow clinical fellows in the patient care setting. As a result, those doing research have the chance to see what patients and their families are going through, as well as see the direct results of their research.

Population(s) Served

The mission of St. Jude Global is to improve the survival rates of children with cancer and other catastrophic diseases worldwide through the sharing of knowledge, technology and organizational skills.

Population(s) Served
Children and youth

Where we work

Goals & Strategy

SOURCE: Self-reported by organization

Learn about the organization's key goals, strategies, capabilities, and progress.

Charting impact

Four powerful questions that require reflection about what really matters - results.

The mission of St. Jude is to advance cures, and means of prevention, for pediatric cancer and other catastrophic diseases through research and treatment. Specifically we wish to increase the cure rates to over 90% for the major forms of childhood cancer and advance research and treatment of specific childhood diseases such as sickle cell disease and pulmonary infectious diseases. When St. Jude opened its doors in 1962, only 20% of children with cancer survived. Today, helped by innovative research at St. Jude, over 80% survive. Consistent with the vision of our founder Danny Thomas, no family ever receives a bill for treatment, travel, housing or food. This allows treatment and research to be conducted at St. Jude in an unsurpassed manner. St. Jude is a world leader in both providing treatment to children and making scientific discoveries that will save the lives of more children in the future.

St. Jude Children's Research Hospital's strategy is to be highly focused on our mission, and provide a culture and environment in which great doctors and scientists can do their best work - that is why we have been so successful. We are not a typical children's hospital, but instead are a specialty hospital focused on pediatric cancer and life-threatening diseases in children including sickle cell disease and HIV/AIDS. This strategy has enabled us to become a world leader in our fields of study. We conduct basic, translational and clinical research designed to find cures, improve diagnosis, enhance treatment outcomes, and minimize adverse effects of treatment for these diseases. Approximately 90% of cancer patients treated at St. Jude are enrolled on one or more of our research studies. We serve as a global resource by sharing our knowledge and discoveries with health care and scientific research professionals around the world. Integral to the success of the organization is our ability to raise the necessary funds to support the mission and accelerate progress.We make our discoveries and treatment innovations widely available to the global healthcare and research communities. We share the primary data from our research freely with those wishing to use this information for research purposes. This includes the data from our Pediatric Cancer Genome Project (PCGP), the largest effort of its type. We also provide online resources like our PCGP Explore and Cure4Kids websites.

St. Jude Children's Research Hospital is the first and only National Cancer Institute-designated comprehensive cancer center devolved solely to children. This designation goes to hospitals that are highly advanced in research, treatment and prevention of cancer. The following capabilities help our organization achieve our stated goals.* World class physicians and researchers.* Highly integrated healthcare teams, providing seamless multi-disciplinary care and research, increasing the speed of discoveries and their translation into new treatments.* Cutting edge research and clinical care facilities.* An efficient fundraising organization that ensures the operation of St. Jude, which relies primarily on the philanthropic support of loyal donors, volunteers and partners.* A committed Board of Governors and Directors.* Collaborations with scientists and physicians around the world.

The most obvious measure of our success are the lifetime of moments we give to children whom we successfully treat. St. Jude has played a significant role in the increased survival for children with pediatric cancer and other catastrophic diseases—not just those we've treated directly, but those who have benefitted from our discoveries. These include: * In 1972, St. Jude achieved a 50% survival rate for patients with acute lymphoblastic leukemia (ALL) through an innovative combination of therapies. At that time, the estimated survival rate was 17% percent. The results revolutionized leukemia treatment worldwide. * St. Jude is credited with the discovery in 1997 that bone marrow transplants from unrelated, genetically matched donors are as effective in treating childhood leukemia as those from patients' siblings who are genetically matched. Currently, St. Jude has the largest pediatric bone marrow transplant program in the country.* In 2006, St. Jude reported 94% survival rates for a group of patients with ALL, a dramatic increase over the 1962 estimated survival rate of just 4 percent. * St. Jude pioneered the elimination of cranial irradiation in treating most leukemia patients, greatly reducing immediate and long-term effects in these patients (2009).* St. Jude was the first hospital in the world to perform gene therapy on a pediatric brain tumor patient (1995). * St. Jude discovered that sickle cell disease can be cured through a bone marrow transplant (1984). This is used in patients where the disease is so severe it justifies the inherent risks of a transplant.* St. Jude is currently engaged in the largest effort in the world to do whole genome sequencing of pediatric cancer tumors. Launched in 2010, the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project holds promise for developing improved approaches to diagnosing and treating childhood cancers. Already, the project has generated more high-coverage, whole genome data than from all other sources combined.Unfortunately, what we still have to accomplish is acutely felt by our physicians and researchers every day: that there are still children who are not cured with today's best treatment. Until all children can be cured, we have not achieved our ultimate goal—to find cures to the diseases we treat so that no child shall die in the dawn of life.


St. Jude Children's Research Hospital

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The people, governance practices, and partners that make the organization tick.


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St. Jude Children's Research Hospital

Board of directors
as of 05/23/2023
SOURCE: Self-reported by organization
Board chair

Ms. Judy A. Habib

Joyce Aboussie

Aboussie & Associates

Anthony Abraham

Anthony Abraham Enterprises

Thomas Abraham

TAGA Enterprises

Susan Aguillard


Mahir Awdeh


Joseph Ayoub

Greenberg Traurig, LLP

Paul Ayoub

Nutter, McClennen & Fish, LLC

James Barkate

Southern Abstracts, Inc.

Martha Beard

Federal Reserve Bank of St. Louis - Memphis Branch

Jack Belz

Belz Enterprises

Kathie Berlin

Community Volunteer

Robert Breit

Meridian Regional Imaging

Terry Burman

Sterling Jewelers, Inc./Signet Group PLC

Stephen Camer


Reo Campian

Community Volunteer

Joseph Corry

East Carolina Univeristy, Brody School of Medicine

Leslie Dale

Community Volunteer

Peter Decker

Decker, Cardon, Thomas, Weintraub & Neskis

Lewis Donelson

Baker, Donleson, Bearman, Caldwell & Berkowitz

Michael Driebe

Community Volunteer

Edward Eissey

Community Volunteer

Hasan Elkhatib

Community Volunteer

George Elias

George Elias, Jr., Esq.

Fred Gattas

Gattas Company

Christopher George

Bay Area Oncology

Hamil Habib

Community Volunteer

Judy Habib

Kelly Habib John

Joseph Haggar

J.M. Haggar, Jr. Investments

Paul Hajar

Hajar Associates

Charles Hajjar

Hajjar Realty & Management Co.

Sam Hamra

Community Volunteer

Fred Harris

Dehyco Company

Theodore Hazer

Community Volunteer

Bruce Hopkins

First Tennessee Bank

Judy Huntley

ESA International

Joseph Hyder

JGH Productions

Joseph Karam

Cedar Enterprises

Richard Karam

Richard J. Karam, Esq.

James Kinney

Community Volunteer

Salli LeVan

Community Volunteer

Judy Lester

Community Volunteer

Albert Lian

Community Volunteer

Donald Mack

Medical Doctor

George Maloof


Jim Maloof

Jim Maloof, Realtor

Paul Marcus

Marcus Capital Management

Mike McCoy

Peoria County Sheriff's Office

James Naifeh

TN State Legislature

David Nimer

Community Volunteer

Talat Othman

Grove Financial

Thomas Penn

Portland Trailblazers

Edward Reed

Medical Doctor

Manal Saab

Community Volunteer

Richard Shadyac

Community Volunteer

Richard Shadyac

Feldesman Tucker Leifer Fidell LLP

Joseph Shaker

Shaker Recruitment Advertising & Communications, Inc.

George Simon

U.S. Equipment Company

Paul Simon

U.S. Group, Inc.

Frederick Smith

FedEx Corporation

Edward Soma

Medical Doctor

Ronald Terry

Community Volunteer

Terre Thomas

Community Volunteer

Tony Thomas

Witt-Thomas Productions

Patt Tigrett

Patt Kerr, Inc.

Richard Unes

Peoria Metro Construction

Paul Wein

Wein, Young, Fenton & Kelsey, P.C.

Thomas Wertz


Robert Younes

Medical Doctor

Robert Younes

Medical Doctor

Ramzi Younis

University of Miami Miller School of Medicine

Tama Zaydon

Oppenheimer & Company

Raymond Zoghby

Zoghby's Department Store/Zoghby's Real Estate Company

Board leadership practices

SOURCE: Self-reported by organization

GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.

  • Board orientation and education
    Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Yes
  • CEO oversight
    Has the board conducted a formal, written assessment of the chief executive within the past year ? Yes
  • Ethics and transparency
    Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes
  • Board composition
    Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Yes
  • Board performance
    Has the board conducted a formal, written self-assessment of its performance within the past three years? No

Organizational demographics

SOURCE: Self-reported; last updated 8/11/2022

Who works and leads organizations that serve our diverse communities? Candid partnered with CHANGE Philanthropy on this demographic section.


The organization's leader identifies as:

Race & ethnicity
Gender identity

Race & ethnicity

No data

Gender identity

No data

Transgender Identity

No data

Sexual orientation

No data


No data